DNA Double-Strand Break Repair Mechanisms Meeting in Paris 2025
Event date:
Friday, Oct 10, 2025 - Friday, Oct 10, 2025 Export event
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Event Date/Time: October 10, 2025, 8:30 am - 5:00 pm (CEST, UTC +2) Time Zone Converter
Location: Salle Dussane, École Normale Supérieure (ENS) - PSL University, 45 rue d'Ulm, 75005 Paris, France
Poster Submissions: pre-printed A0 vertical posters
Please complete this online form to confirm your participation in the event and to submit your poster.
Organizing Committee:
Anđela Radovanović, ENS-PSL Paris, France
Vincent Morin, ENS-PSL, Paris, France
Afra Sabei, Université Paris Cité, Paris, France
Sophia Missoury, Institut Pasteur, Paris, France
We are excited to invite you to a one-day Biophysical Society (BPS) networking event at the École Normale Supérieure (ENS) - PSL University, focused on the intriguing world of DNA double-strand break repair mechanisms. The aim of this event is to present and discuss DNA repair from multiple perspectives, by exploring different repair pathways (such as NHEJ and HR) and a variety of experimental approaches.
The program will feature scientific talks from experts in the fields, followed by interactive discussions, as well as a poster-session and flash talks showcasing research from early-career scientists.
This event is open to students, early-career scientists, and senior researchers alike, offering a welcoming space for exchanging ideas, learning and fostering new collaborations.
We hope to see you there!
Event Speakers
Dr. Pascale Bertrand, Institut de biologie François Jacob
Dr. Chantal Prévost, Institut de Biologie Physico-Chimique
Dr. Angela Taddei, Institut Curie
Dr. Ludovic Sauguet, Institut Pasteur
Dr. Pauline Dupaigne, Gustave Roussy
Dr. Raphael Ceccaldi, Institut Curie
Dr. Julien Bischerour, Institut de biologie intégrative de la cellule (I2BC)
Dr. Eric Coic,Institut de biologie François Jacob
Dr. Terence Strick, ENS-PSL, Paris
Event Schedule
All times in CEST, GMT+02:00
Program
| 8:30 - 8:55h |
Registration |
| 8:55 - 9:00h |
Welcoming Remarks |
| 9:00 - 9:30h |
Dr. Julien Bischerour
What Role Do NHEJ Factors Play in the Programmed Elimination of DNA in Paramecium tetraurelia? |
| 9:30 - 10:00h |
Dr. Terence Strick
NHEJ: From Bacteria to Humans |
| 10:00 - 10:15h |
Coffee Break |
| 10:15 - 10:45h |
Dr. Ludovic Sauguet
Uncovering the Molecular Mechanisms of Homologous Recombination in Archaea |
| 10:45 - 11:15h |
Dr. Pascale Bertrand
Lamin B1 and Double-Strand Break Repair |
| 11:15 - 12:00h |
Flash Talks (young researchers introducing their projects and posters) |
| 12:00 - 13:00h |
Lunch Break |
| 13:00 - 14:00h |
Poster Session (young researchers presenting) |
| 14:00 - 14:30h |
Dr. Chantal Prévost
How RecA Nucleoprotein Filaments Respond to Internal Mechanical Stress: A Study via Numerical Simulation |
| 14:30 - 15:00h |
Dr. Angela Taddei
Structure and Dynamics of Rad51 Filaments during Homology Search in Living Yeast |
| 15:00 - 15:15h |
Coffee Break |
| 15:15 - 15:45h |
Dr. Pauline Dupaigne
Structural Basis for DMC1 Presynaptic Filament Regulation and Interaction with BRCA2 and Other Partners during Meiotic Homologous Recombination |
| 15:45 - 16:15h |
Dr. Raphael Ceccaldi
How Homologous Recombination (HR)-deficient Tumors Survive Genomic Instability |
| 16:15 - 16:45h |
Dr. Eric Coic
Rad52 C-Terminus Acts as an Assembly Chaperone and Stabilizes Rad51 Filaments through a Large 85-Residue Segment in vivo |
| 16:45 - 17:00h |
Closing Remarks |
Flash Talks
1. Julien KARAZI
“Understanding the Ku-WRN duo for the maintenance of genome integrity” |
2. Timea MARTON
“Polymerase theta repairs persistent G1-induced DNA breaks in S-phase during antigen receptor gene diversification” |
3. Suliane QUILLERÉ
“Moss BRCA2 interacts with recombinases and ssDNA in DNA repair” |
Posters
1. Emilie NAVARRO
“Rad51 filament regulation by Srs2 and Rad52 in homologous recombination in Saccharomyces cerevisiae” |
2. Maud Lagier
"Investigating the coordination of of double-strand break ends during homologous recombination in living budding yeast" |
3. Reem KARAKI
“The role of protein disorder and liquid-liquid phase separation in the repair of DNA double-strand breaks by non-homologous end joining” |
4. Suliane QUILLERÉ
“Moss BRCA2 interacts with recombinases and ssDNA in DNA repair” |
5. Lucas KHOURY
“Role of DNA-PKcs in the NHEJ double strand break repair mechanism” |
6. Jaouen TRAN-RAJAU
“Beyond single molecule: magnetic tweezers for drug screening” |
7. Fadma LAKHAL
“Structural and functional study of the Rad51 nucleofilament in budding yeast” |
8. Marie-Alice MINASSIAN
“The Role of Rad51 Paralogs in Recombinational Repair in S. cerevisiae during mitosis” |
9. Marie IMBERT
“Structural snapshots of D-loop formation by RadA highlight the evolutionary conservation of HR in Archaea and in Eukaryotes” |
10. Laurent MALOISEL
"Structural insights into the Shu and Rad55-Rad57 complexes associated with Rad51 nucleofilaments highlight their role in homologous recombination" |
11. Cloé DEHOURS
"Stiff Matters: Extracellular Matrix Rigidity and DNA Repair Dynamics in Cancer" |