Biophysical Journal Award
Biophysical Journal (BJ) is pleased to announce the new
Biophysical Journal Paper of the Year Award. The award will be presented
to the corresponding author of an outstanding paper published in the
Journal during the previous 12 months beginning with January 2014
submissions. To qualify, the corresponding author must have received
his/her PhD or MD within the past 12 years. The award will spotlight the
high-quality work of young investigators who publish in BJ.
The award will include a $1,000 prize and a speaking position at the Annual Meeting Awards Symposium.
research articles will be nominated by each of the Associate Editors
and the award recipient will be selected by a committee of Associate
Editors and the Editor-in Chief.
New & Notables
Each month a few papers are highlighted in BJ with
a New & Notable article. These are commentaries in which the author
can highlight a point, question, or controversy raised in the paper it
discusses. Following is a list of New & Notable articles recently
published. Visit www.biophysj.org to read the articles.
Capsid Deformations Reveal Complex Mechano-Chemistry, Konstantin I. Popov, Garegin A. Papoian, which highlights the paper: Structural
Transitions and Energy Landscape for Cowpea Chlorotic Mottle Virus
Capsid Mechanics from Nanomanipulation in Vitro and in Silico, Olga Kononova, Joost Snijder, Melanie Brasch, Jeroen Cornelissen, Ruxandra I. Dima, Kenneth A. Marx, Gijs J.L. Wuite, Wouter H. Roos, Valeri Barsegov.
Dynamic DNA Underpins Chromosome Dynamics, Andrew Travers, which highlights the paper: Temperature Dependence of the DNA Double Helix at the Nanoscale: Structure, Elasticity, and Fluctuations, Sam Meyer, Daniel Jost, Nikos Theodorakopoulos, Michel Peyrard, Richard Lavery, Ralf Everaers.
Is Potassium a Ubiquitous Mediator of Vasodilation in the Central Nervous System?, Lane K. Bekar, Maiken Nedergaard, which highlights the paper: Potassium Buffering in the Neurovascular Unit: Models and Sensitivity Analysis, Alexandra Witthoft, Jessica A. Filosa, George Em Karniadakis.
The following Review was also published in November: FRET Spectrometry: A New Tool for the Determination of Protein Quaternary Structure in Living Cells, Valerică Raicu, Deo R. Singh.
Know the Editors
Each month this section of the Newsletter highlights BJ editors.
Editor for Membranes Section
Q: What is your area of research?
research interests lie at the interface of cell biology and biophysics.
A major goal of my research program has been to elucidate the
fundamental structural and dynamic properties of membrane domains in
cells. To this end, my group has worked to develop biophysical
approaches to study membrane domains and protein and lipid dynamics in
cells using fluorescence microscopy and live cell imaging, while at the
same time maintaining an interest in how domains function at the
cellular level. Our recent work has focused on understanding the nature
of domains formed upon binding of the raft crosslinker cholera toxin to
cell membranes, as well as investigating how these domains regulate the
uptake of cholera toxin into cells. To complement our work in cells,
we have begun to extend our work to model membrane systems, including
giant unilamellar vesicles and plasma membrane-derived vesicles. We also
use diffusion measurements as a tool to study protein complexes in
their native environment in cells. In collaboration with
biomathematicians, we have developed methods to quantifying diffusion
and reaction-diffusion using quantitative fluorescence microscopy
approaches. Using these tools, we have addressed a number of questions
in diverse areas of cell biology, including the principles that govern
the reversible binding of proteins to DNA and membranes in cells and the
size and stoichiometry of protein complexes in the autophagy pathway.