Drug Discovery for Ion Channels XII

Drug Discovery for Ion Channels XII

Friday, February 24, 2012
San Diego Convention Center
Room 28AB
9:00 AM - 5:00 PM

On-site registration is available for this meeting. To register, you may fill out a registration form in advance and bring it to the registration table in front of Room 28. Forms will also be available on-site. Registration will open at 8:00 AM on Friday.


Since the inaugural “Drug Discovery for Ion Channels” satellite meeting, there have been many advances in ion channel drug discovery including new instrumentation and techniques.  This year’s Satellite Meeting will review the advances in automated electrophysiology and other emerging technologies and the impact they’ve had on ion channel drug discovery.  This year’s meeting will highlight presentations from users of automated electrophysiology instrumentation as well as other speakers in the field of ion channel drug discovery.


8:00 AM - 9:00 AM Registration/Introduction
9:00 AM - 9:40 AM Keynote Speaker: Stuart Lipton, Sanford-Burnham Medical Research Institute
A Success in Drug Development for Academia:  NMDA-type Glutamate Receptor Antagonists
9:40 AM - 10:10 AM Ruth L. Martin, Abbott
Nav 1.5 Barracuda Assay Development - Successes and Issues
10:10 AM - 10:40 AM
Pamela Tranter, Novartis, United Kingdom
Automated Electrophysiology Assays to Profile Chloride Channel Modulators
10:40 AM - 11:00 AM Break
11:00 AM - 11:30 AM John D. Graef, Targacept, Inc.
A Method for Bidirectional Solution Exchange – “Liquid bullet” Applications of Acetylcholine to Alpha7 Nicotinic Receptors
11:30 AM - 12:00 PM Henning Draheim, BoehringerIngelheimPharma GmbH & Co. KG
Finding your Right APC device – A Case Study
12:00 PM - 12:30 PM
Jerod Denton, Vanderbilt University
Development of automated patch clamp methods for studies of Kir4.1 potassium channel pharmacology using the IonFlux HT  
12:30 PM - 1:30 PM Lunch Break
1:30 PM - 2:10 PM Keynote Speaker: Alan Wickenden, Janssen Research and Development, Johnson and Johnson
Ion Channels Screening: Past, Present, and Future
2:10 PM - 2:40 PM
Chris Fanger, Hydra Biosciences
The Patchliner as Flexible Tool for Safety Screening and Target Validation
2:40 PM - 3:10 PM
Glenn E. Kirsh, ChanTest Corporation
Validation of High Thoroughput Automated Patch Clamp Assays for Voltage-gated Na+ Channels Screening
3:10 PM - 3:30 PM
3:30 PM - 4:00 PM Speaker from Cellectricon
4:00 PM - 4:30 PM Jean Francois Rolland
In Silico screening and Automated Patch-Clamp: toward a perfect cocktail for Ion Channel Drug Discovery
4:30 PM - 5:00 PM
Jinliang Sui, Flatley Labs
Advancing High Throughput Screening of CFTR Modulators with Human Epithelial Cell Lines
5:00 PM - 5:15 PM Closing Remarks, Chris Mathes, Co-Chair


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