Final Program

 

Tuesday, July 5, 2011

5:00 - 6:00 PM 
Reception

6:00 - 7:00 PM  
Dinner & Opening Remarks

Evening Session
DNA Packaging in Prokaryotes

Chair: Linda J. Kenney, University of Illinois, Chicago

7:00 - 7:10 PM
Chair's Opening Remarks

7:10 - 7:40 PM
3-D Structural Organization of DNA in Bacterial Chromosome
Sankar Adhya, National Institutes of Health

7:40 - 8:10 PM
The 3-8 Body Problem in E. coli/Salmonella Chromosome Dynamics
Patrick Higgins, University of Alabama at Birmingham

8:10 - 8:25 PM
Coffee Break

8: 25 - 8:55 PM
H-NS Forms a Superhelical Protein Scaffold for DNA Condensation
John Ladbury, University of Texas, Houston

8:55 - 9:25 PM
Similarities and Distinctions of H-NS-like Proteins in DNA Binding
Jie Yan, National University of Singapore, Singapore

9:25 - 9:40 PM 
The Effect of Salt and Temperature on the H-NS Dimerization Domain
Jocelyne Vreede, University of Amsterdam, The Netherlands

Wednesday, July 6, 2011

7:30 - 8:30 AM
Breakfast

Morning Session
DNA: Protein Condensation and Energetics

Chair: Corey O'Hern, Yale University

9:00 - 9:10 AM
Chair's Opening Remarks

9:10 - 9:40 AM
The Physics of DNA Packaging: The Hidden Life of a Macromolecular Celebrity
Rob Phillips, California Institute of Technology

9:40 - 10:10 AM
Encapsidation of Single-stranded RNA by Viral Proteins
Robijn Bruinsma, University of California, Los Angeles

10:10 - 10:25 AM
Crowding Induced Structural Characterizations of Chromosome Model Studied with Brownian Dynamic Simulations
Igal Szleifer, Northwestern University

10:25 - 10:40 AM
Coffee Break

10:40 - 11:10 AM
Forced Unravelling of DNA-H1 Toroids
Simon Mochrie, Yale University

11:10 - 11:40 AM
Unlocking Nucleosome Dynamics with Histone Post-translational Modifications
Michael Poirier, Ohio State University

12:00 - 1:00 PM
Lunch

2:00 - 5:00 PM
Poster Session

6:00 - 7:00 PM
Dinner

Evening Session
Nucleosome Structure and Stability

Chair: Lynne Regan, Yale University

7:00 - 7:10 PM
Chair’s Opening Remarks

7:10 - 7: 40 PM
A Genomic Code for Nucleosome Positioning from Archaebacteria to Humans
Jonathan Widom, Northwestern University

7:40 - 7:55 PM
Structure and Stability of Nuclesomes Studied by spFRET and Thermal Denaturation
Katalin Toth, German Cancer Research Center, Germany

7:55 - 8:25 PM
Chromatin Architectural Proteins and Their Interactions with Nucleosomes
Karolin Luger, Colorado State University  

8:25 - 8:40 PM
Coffee Break

8:40 - 8:55 PM
Electrostatic and Molecular Mechanisms in Chromatin Folding and Self-association and the Effects of Histone H4 Tail Acetylation
Lars Nordenskiod, Nanyang Technological University, Singapore

8:55 - 9:25 PM
Marking and Maintaining Centromere Location and the Histone Variant CENP-A
Ben Black, University of Pennsylvania

9:25 - 9:40 PM
Nucleosome Dynamics Studied by All Atom and Coarse Grain Molecular Dynamics Simulations
Jorg Langowski, German Cancer Research Center, Germany

Thursday, July 7, 2011

7:30 - 8:30 AM
Breakfast

Morning Session
Nucleosome Assembly and Mechanics

Chair: Robijn Bruinsma, University of California, Los Angeles

9:00 - 9:10 AM
Chair’s Opening Remarks

9:10 - 9:40 AM
Throwing a Curve at DNA: DNA and Histone Chaperone Structure and Activity
Mair Churchill, University of Colorado, Denver

9:40 - 9:55 AM
Indentification of a Rapidly Formed Non-nucleosomal Histone-DNA Intermediate That Is Converted Into Chromatin by ACF
Sharon Torigoe, University of California, San Diego

9:55 - 10:25 AM
The Interplay of Chromatin and the Cytoskeleton
Megan King, Yale University

10:25 - 10:40
Coffee Break

10:40 - 11:10 AM
Euler's Elastica and Their Applications to DNA, Nucleosomes and Chromatin Fibers
Helmut Schiessel, Leiden University, The Netherlands

11:10 - 11:40 AM
Spatio-temporal Organization of Chromosome Assembly in Eukaryotes
G. V. Shivashankar, National University of Singapore, Singapore

12:00 - 1:00 PM
Lunch

2:00 - 5:00 PM
Poster Session

6:00 - 7:00 PM
Dinner

Evening Session
Beyond the Nucleosome – Higher Order Structures

Chair: G.V. Shivashankar, National University of Singapore, Singapore

7:00 - 7:10 PM
Chair’s Opening Remarks 

7:10 - 7:40 PM
Unraveling Chromatin Structure and Dynamics by Force
John van Noort, Leiden University, The Netherlands

7:40 - 7:55 PM
Function and Formation of the Nucleosome Depleted Region
Lu Bai, Rockefeller University

7:55 - 8:10 PM
Chromodomain-mediated Oligomerization of HP1 Suggests a Nucleosome Bridging Mechanism for Heterochromatin Assembly
Daniele Canzio, University of California, San Francisco

8:10 - 8:25 PM
Coffee Break

8:25 - 8:40 PM
E. coli Chromosome Morphology, Mechanical Properties and Dynamics at High Resolution in Living Cells
Jay Fisher, Harvard University

8:40 - 8:55 PM
Ordered Arrays of Single Elongated Chromatin Fragments: Towards a Two-dimensional Mapping and Analysis of Epigenetic Marks
Aline Cerf, Cornell University

8:55 - 9:10 PM
A Genome-Wide Approach to Transcriptional Reveals Novel Thyroid Hormone Regulatory Mechanisms
Stephen Ayers, Methodist Hospital Research Institute

9:10 - 9:25 PM
Theoretical Modeling of the Organization, Dynamics, and Regulation of Chromatin
Gaurav Arya, University of California, San Diego

Friday, July 8, 2011

7:30 - 8:30 AM
Breakfast

Morning Session
In Vivo Studies of DNA-Protein Interactions

Chair: Sankar Adhya, National Institutes of Health

9:00 - 9:10 AM
Chair’s Opening Remarks

9:10 - 9:40 AM
Quantifying Protein Interactions and Stochasticity of Gene Expression in Live Cells by Fluorescence Fluctuation
Catherine Royer, INSERM, The University of Montpellier, France

9:40 - 10:10 AM
Single Molecule FRET Studies of Gene Expression in Cells
Sunney Xie, Harvard University

10:10 - 10:25 AM
Chromatin Compaction Regulates EGFP Diffusion and Localization During the Cell Cycle
Elizabeth Hinde, University of California, Irvine

10:25 - 10:40 AM
Coffee Break

10:40 - 11:10 AM
Metabolic Control of Access to the Chromosome in the Test Tube and the Cell
Dorothy Beckett, University of Maryland

11:10 - 11:25 AM
Single Molecule Analysis of Yeast Genes in Different Transcriptional State
Christopher Brown, University of California, Santa Cruz

11:25 - 11:30 AM
Closing Remarks – The Organizing Committee
Linda J. Kenney, University of Illinois, Chicago
Corey O'Hern, Yale University
Lynne Regan, Yale University

12:00 - 1:00 PM
Lunch

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