Rohit Pappu, Washington University, St. Louis, Subgroup Chair

REGULATION AND UTILIZATION OF DISORDER IN VIVO

Elisar Barbar, Oregon State University, and Huang-Xiang Zhou, Florida State University

1:00 PM
WELCOME
Rohit Pappu, Washington University, St. Louis, Subgroup Chair

1:05 PM
Postdoc Speaker 1: Ariele Viacava Follis, St. Jude Children's Hospital,
PROBING THE ROLE OF INTRINSICALLY DISORDERED DOMAINS IN THE p53-Bcl-xL
INTERACTION

Session 1

Elisar Barbar, Oregon State University, Chair

1:15 PM
Keynote Lecture
ON THE ROLE OF NATIVELY UNFOLDED PROTEINS IN NUCLEOCYTOPLASMIC TRANSPORT
Brian Chait, Rockefeller University

2:05 PM
BINDING KINETICS OF INTRINSICALLY DISORDERED PROTEINS WITH THEIR TARGETS
Huan-Xiang Zhou, Florida State University

2:30 PM
THE ROLE OF UNSTRUCTURED REGIONS IN PROTEINS AS PART OF THE PROTEASOME DEGRADATION SIGNAL
Andreas Matouschek, Northwestern University

2:55 PM
IDP Subgroup Postdoctoral Speaker Award Recipient
Speaker to be announced

3:10 PM
ACTIVATION OF A REDOX-REGULATED CHAPERONE BY OXIDATIVE PROTEIN UNFOLDING
Ursula Jakob, University of Michigan

3:35 PM
Break

Session 2

Huan-Xiang Zhou, Florida State University, Chair

4:00 PM
INTRINSICALLY UNSTRUCTURED PROTEINS: REGULATION AND DISEASE
M. Madan Babu, University of Cambridge, United Kingdom

4:25 PM
MISFOLDING AND MEMBRANE INTERACTION OF AMYLOIDOGENIC PROTEINS
Ralf Langen, University of Southern California

4:50 PM
SEARCHING DNA: THE SIGNIFICANCE OF DISORDERED TAILS
Yakov Levy, Weizmann Institute, Rehovot, Israel

5:15 PM
INTRINSICALLY DISORDERED HISTONE TAILS: INTEGRATORS OF MULTIPLE SIGNALING PATHWAYS IN CHROMATIN AND GENE REGULATION
Cheryl Arrowsmith, University of Toronto, Canada

5:40 PM
Postdoc Speaker 2: Chung-Ke Chang, National Taiwan Normal University, EFFECT
OF INTRINSICALLY DISORDERED REGIONS OF SARS CORONAVICAPSID FORMATION

5:55 PM
STRUCTURE AND EVOLUTION OF INTRINSICALLY DISORDERED PROTEINS
Gary Daughdrill, University of South Florida