Biophysical Journal Corner

 Biophysical Journal Award

Biophysical Journal (BJ) is pleased to announce the new Biophysical Journal Paper of the Year Award. The award will be presented to the corresponding author of an outstanding paper published in the Journal during the previous 12 months beginning with January 2014 submissions. To qualify, the corresponding author must have received his/her PhD or MD within the past 12 years. The award will spotlight the high-quality work of young investigators who publish in BJ.

The award will include a $1,000 prize and a speaking position at the Annual Meeting Awards Symposium.

Regular research articles will be nominated by each of the Associate Editors and the award recipient will be selected by a committee of Associate Editors and the Editor-in Chief.

New & Notables

Each month a few papers are highlighted in BJ with a New & Notable article. These are commentaries in which the author can highlight a point, question, or controversy raised in the paper it discusses. Following is a list of New & Notable articles recently published. Visit www.biophysj.org to read the articles.

Capsid Deformations Reveal Complex Mechano-Chemistry, Konstantin I. Popov, Garegin A. Papoian, which highlights the paper: Structural Transitions and Energy Landscape for Cowpea Chlorotic Mottle Virus Capsid Mechanics from Nanomanipulation in Vitro and in Silico, Olga Kononova, Joost Snijder, Melanie Brasch, Jeroen Cornelissen, Ruxandra I. Dima, Kenneth A. Marx, Gijs J.L. Wuite, Wouter H. Roos, Valeri Barsegov.

Dynamic DNA Underpins Chromosome Dynamics, Andrew Travers, which highlights the paper: Temperature Dependence of the DNA Double Helix at the Nanoscale: Structure, Elasticity, and Fluctuations, Sam Meyer, Daniel Jost, Nikos Theodorakopoulos, Michel Peyrard, Richard Lavery, Ralf Everaers.

Is Potassium a Ubiquitous Mediator of Vasodilation in the Central Nervous System?, Lane K. Bekar, Maiken Nedergaard, which highlights the paper: Potassium Buffering in the Neurovascular Unit: Models and Sensitivity Analysis, Alexandra Witthoft, Jessica A. Filosa, George Em Karniadakis.

Reviews

The following Review was also published in November: FRET Spectrometry: A New Tool for the Determination of Protein Quaternary Structure in Living Cells, Valerică Raicu, Deo R. Singh.

Know the Editors

Each month this section of the Newsletter highlights BJ editors.

Anne Kenworthy
Vanderbilt University
Editor for Membranes Section

 

 

 

 

 

 Q: What is your area of research?
My research interests lie at the interface of cell biology and biophysics. A major goal of my research program has been to elucidate the fundamental structural and dynamic properties of membrane domains in cells. To this end, my group has worked to develop biophysical approaches to study membrane domains and protein and lipid dynamics in cells using fluorescence microscopy and live cell imaging, while at the same time maintaining an interest in how domains function at the cellular level. Our recent work has focused on understanding the nature of domains formed upon binding of the raft crosslinker cholera toxin to cell membranes, as well as investigating how these domains regulate the uptake of cholera toxin into cells. To complement our work in cells, we have begun to extend our work to model membrane systems, including giant unilamellar vesicles and plasma membrane-derived vesicles. We also use diffusion measurements as a tool to study protein complexes in their native environment in cells. In collaboration with biomathematicians, we have developed methods to quantifying diffusion and reaction-diffusion using quantitative fluorescence microscopy approaches. Using these tools, we have addressed a number of questions in diverse areas of cell biology, including the principles that govern the reversible binding of proteins to DNA and membranes in cells and the size and stoichiometry of protein complexes in the autophagy pathway.