Sunney Xie

Peking University

From Single-Molecule Biophysics to Single-Cell Genomics: When Stochasticity Meets Precision 

Monday, February 17, 8:00 PM
San Diego Convention Center

Being named the 2021 Biophysical Society Lecturer is the highest annual award bestowed by the Biophysical Society. In addition to presenting the  Annual Biophysical Society Lecture, the recipient provides a molecule or figure that depicts his/her research. That figure is used in the background design for that year’s Annual Meeting print and web announcements.  

Xiaoliang Sunney Xie, Lee Shau-kee Professor at Peking University and Director of Biomedical Pioneering Innovation Center (BIOPIC), has been selected as the 2020 BPS Lecturer at the Biophysical Society 64th Annual Meeting in San Diego, California. Previously, Dr. Xie received the Biophysical Society Founders Award. He is a Member of the National Academy of Sciences as well as a Member of the National Academy of Medicine, among several other prestigious honors. He has made major contributions to the fields of single-molecule enzymology and biophysical chemistry and, along with his research group, pioneered the development of coherent Raman scattering microscopy and single cell whole genome sequencing. Recently named Director of the Beijing Advanced Innovation Center for Genomics (ICG), Xie has made significant advances in single cell genomics. In particular, his inventions have been used for preimplantation genetic testing in in vitro fertilization.

The Image: Combinatorial transcription factor groups: Genome-wide binding sites of three individual transcription factors (EGR1, SP1, and YY1) and their pairwise combinations on a cross section of the 3D genome of a human B cell.