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The Biophysical Society's Subgroups hold symposia that allow attendees to meet and interact within focused areas. This year’s subgroup symposia will be held on the first day of the Annual Meeting, Saturday, March 2, 2019. The Saturday Subgroup programs are heavily attended and include exciting scientific symposia, awards presentations, student and postdoc talks, and business meetings, which are open to members of each subgroup. 

To view a subgroup's 2019 symposium program, click on the subgroup's name. 
Subgroup programming details will be posted as they become available. 

For those attending subgroup symposia, registration will be open on Friday and Saturday for badge pick-up prior to the subgroup sessions. Registration for the Annual Meeting is required to attend the subgroup symposia.

 

For more information on subgroups and how to join, click here

Bioenergetics, Mitochondria, and Metabolism

Subgroup Co-Chairs: Elizabeth Jones, Yale University and George Porter, University of Rochester

Program Co-Chairs: William A. Cramer and Karin Busch

Baltimore Convention Center Rooms: 324, 325, 326

Business Meeting: 5:00 PM - 6:00 PM

Speakers

Morning Session: Structure-Function of Mitochondrial Super-Complexes 

9:00 - 9:10 AM William A. Cramer, Purdue University, USA, Introduction:  A New View of Organelle Energy Transduction: Super-Complexes

9:10 - 9:40 AM Werner Kühlbrandt, Max Planck Institute for Biophysics, Germany, New mechanistic insights from cryoEM structures of ATP synthases​

9:40 - 10:10 AM William Dowhan, University of Texas Health Science Center, USA, A requirement for cardiolipin in the organization and function of mitochondrial super-complexes

10:10 - 10:40 AM Rosemary Stuart, Marquette University, USA, Rcf1 and Rcf2: central role in cytochrome c oxidase enzymology and support of the proton motive force

10:55 - 11:25 AM Robert Gennis, University of Illinois, USA, Structure of the Alternative Complex III from Flavobacterium Johnsoniae within a Supercomplex with Cytochrome aa3

11:25 - 11:55 AM Helmut Kirchhoff, Washington State University, USA, Quinone Diffusion in Photosynthetic Membranes: Challenges Caused by Complex Membrane Architectures

 

Afternoon Session: Metabolic Approaches for Longevity and Disease Treatment (with a Focus on Ketone Bodies)

1:35 - 1:45 PM Elena N. Dedkova, University of California - Davis, USA, Introduction

1:45 - 2:15 PM Carl E. Stafstrom, Johns Hopkins University, USA, Ketogenic Diet: Evidence for Metabolic Control of Neuronal Excitability and Seizures

2:15 - 2:45 PM Peter A. Crawford, University of Minnesota, USA, Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics

2:45 - 3:15 PM Daniel P. Kelly, University of Pennsylvania, USA, Ketone bodies as a therapeutic strategy for heart failure

3:30 - 4:00 PM Kieran Clarke, University of Oxford, United Kingdom, Novel ketone monoester for human exercise and cognition: Why, how and when

4:00 - 4:30 PM Eric Verdin, Buck Institute for Research on Aging, USA, Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice

4:30 - 5:00 PM Elena N. Dedkova, University of California - Davis, USA, Ketone Bodies and their Polymers in Heart Failure and Type 2 Diabetes: Lessons Learned from the Ketone Ester Diet

Bioengineering

 

Subgroup Chair: Amir Farnoud, Ohio University 

Baltimore Convention Center Rooms: 327, 328, and 329 

Business Meeting: 10:55 AM - 11:10 AM

Speakers

9:00 - 9:10 AM Amir Farnoud, Opening Remarks

9:10 - 9:40 AM Ka Yee Lee, University of Chicago, USA, Nanoparticle-supported lipid bilayers: A platform for interrogating lipid-protein interactions at highly curved surfaces

9:40 - 10:10 AM Susan Daniel, Cornell University, USA, Golgi-on-a-Chip for the Cell-free Bio-nanomanufacturing of Protein Therapeutics

10:10 - 10:40 AM Mark Uline, University of South Carolina, USA, Utilizing the Synergistic Power of Molecular Theory and Molecular Simulation to Solve Bioengineering Problems

11:10 - 11:40 AM Daniel Hammer, University of Pennsylvania, USA, Upstream Migration of Amoeboid Cells: Dynamics and Memory

11:40 AM - 12:10 PM Jennifer Elisseeff, Johns Hopkins University, USA, Immunoengineering in Regenerative Medicine

12:30 PM Amir Farnoud, Closing Remarks


 

Biological Fluorescence

Subgroup Chair: Paul Wiseman, McGill University, Canada

Baltimore Convention Center Rooms: 309 and 310

Business Meeting: 3:15 PM - 3:25 PM

Speakers

1:00 - 1:05 PM Paul Wiseman, Opening Remarks

1:05 - 1:35 PM Don Lamb, Ludwig Maximilian University of Munich, Germany, The Coming of Age: Fluorescence Investigations of the Early Childhood of HIV Particles

1:35 - 2:05 PM Ralf Jungmann, Max Planck Institute of Biochemistry, Martinsried, Germany, Super-resolution Microscopy with DNA Molecules: Towards Localizomics

2:05 - 2:35 PM Alessandra Cambi, Radboud University, The Netherlands, Multimodal Microscopy Reveals Stiffness-dependent Nanoscale Remodeling of Different Actin Modules during Cell Protrusion

2:35 - 3:05 PM Bin Wu, Johns Hopkins University, USA, Visualizing Translation Dynamics of Single mRNAs in Live Cells

3:25 - 3:55 PM Luke Lavis, Janelia Research Campus, USA, Building Brighter Fluorophores for Advanced Biological Imaging

3:55 - 4:25 PM Elizabeth Hillman, Columbia University, USA, High Speed 3D in-Vivo Fluorescence Microscopy

4:25 - 4:45 PM Rapid Fire Talks

4:45 - 5:00 PM Young Fluorescence Investigator Award & Lecture

5:00 - 5:15 PM Gregorio Weber Award & Lecture

5:15 PM Diane Lidke, Closing Remarks

Biopolymers in Vivo

Subgroup Chair: Simon Ebbinghaus, Technische Universität Braunschweig, Germany

Baltimore Convention Center Rooms: 301, 302 and 303

Business Meeting: Noon - 1:00 PM

Speakers

1:00 - 1:05  PM Opening Remarks

1:05 - 1:50 PM James Bruce, University of Washington, USA, Exploring the in Vivo Interactome

1:50 - 2:20 PM Junior Faculty Award Winner: Lisa Jones, University of Maryland School of Pharmacy, Protein Footprinting Coupled with Mass Spectrometry for In-Cell Protein Analysis

2:20 - 2:50 PM Mark Leake, York University, United Kingdom, Illuminating the Black Box of DNA-Protein Interactions

2:50 - 3:05 PM Student/Postdoc Talk: Matthew D. Dalphin, The Earliest Stages of a Protein's Life Influences its Long-Term Solubility and Structural Accuracy

3:05 - 3:35 PM Kerwyn C. Huang, Stanford University, USA, Conformational Dynamics of a Bacterial Actin Filament Predict in Vivo Filament Length

4:00 - 4:30 PM Danny Hatters, University of Melbourne, Australia, Proteome Aggregation Patterns under Proteostasis Stress as Signatures for Understanding Huntington’s Disease

4:30 - 4:45 PM Student/Postdoc Talk: Gregory Dinon, A High-Throughput Approach to Phase Separation of Disordered Proteins

4:45 - 5:15 PM Shana Elbaum-Garfinkle, City University of New York, USA, Protein Phase Separation and Emergent Material Properties

5:15 - 6:05 PM Lucy Shapiro, Stanford University, USA, A Bacterial Membraneless Organelle Sequesters a Signaling Pathway that Drives Spatial Regulation of Cell Function

Cell Biophysics

Subgroup Chair:  Jie Xiao, Johns Hopkins University School of Medicine   

Baltimore Convention Center Rooms:  307 and 308

Business Meeting:  5:45 PM - 6:15 PM

Speakers:  

1:00 - 1:30 PM Haw Yang, Princeton University, USA, Unsupervised Statistical Learning of the Structural and Kinetic Elements in Multi-Resolution Dynamics

1:30 - 2:00 PM Kandice Tanner, National Institutes of Health, USA, High Frequency Active Microrheology Reveals Mismatch in 3D Tumor Intracellular and Extracellular Matrix Viscoelasticity

2:00 - 2:30 PM Liedewij Laan, Delft University of Technology, The Netherlands, Evolutionary Self-organization: Lessons from the Yeast Polarization Machinery

2:30 - 3:00 PM Christine Payne, Duke University, USA, TiO2 Nanoparticle-cell Interactions: Importance of Protein Corona

3:00 - 3:15 PM Javier Buceta, Lehigh University, USA, Scutoids: understanding the 3D packing of curved epithelia

3:45 - 4:15 PM Johan Elf, Uppsala University, Sweden, Genome-wide Single Cell Biophysics

4:15 - 4:45 PM Jung-chi Liao, Academia Sinica IAMS, Taiwan, Centriole Interaction Infrastructure Revealed by Superresolution Microscopy

4:45 - 5:15 PM David Rueda, Imperial College School of Medicine, United Kingdom, Imaging Cellular RNAs at Single Molecule Resolution with Fluorgenic RNA-Mango Aptamers      

5:15 - 5:30 PM 

5:30 - 5:45 PM Anna L. Duncan, Oxford University, United Kingdom, How nanoscale protein interactions determine the mesoscale dynamic organization of membrane proteins

Cryo-EM

Subgroup Chair: Jenny Hinshaw, National Institutes of Health    

Program Co-Chairs: Jason Mears and Gabriel Lander

Baltimore Convention Center Rooms: Ballroom III

Business Meeting: 8:20 PM - 8:35 PM

Speakers

7:00 - 7:05 PM Opening Remarks

7:05 - 7:30 PM Julia Mahamid, European Molecular Biology Laboratory, Germany, Molecular Views into Cellular Function by in situ Cryo-Electron Tomography

7:30 - 7:55 PM Alex Noble, New York Structural Biology Center, USA, Cryo-tomography Methods and Spotition

7:55 - 8:20 PM Alberto Bartesaghi, Duke University, USA, Streamlining Workflows for Structure Determination by Single Particle Cryo-EM

8:35 - 9:00 PM Thomas Marlovits, Center for Structural Systems Biology, Hamburg, Germany, StarMap: Rosetta Refinement Controlled from Chimera 

9:00 - 9:25 PM Scott Stagg, Florida State University, USA, Throughput and Resolution with a Next Generation Direct Detector

9:25 - 10:00 PM Tim Grant, Howard Hughes Medical Institute - Janelia Campus, USA, New Developments in the cisTEM Software Package


 

Exocytosis & Endocytosis

Subgroup Chair: Amy Lee, University of Iowa

Baltimore Convention Center Rooms: 331 and 332

Business Meeting: 4:05 PM - 4:30 PM     

Speakers

1:00 - 1:05 Amy Lee, Opening Remarks

2:05 - 2:40 PM Ira Milosevic, European Neuroscience Institute, University Medical Center Göttingen, Germany, Regulation of Vesicle Acidification at the Neuronal Synapse

2:55 - 3:30 PM Nils Brose, Max Planck Institute of Experimental Medicine, Germany, Synaptic Vesicle Priming and the Unique Features of Regulated Exocytosis at Nerve Cell Synapses

3:30 - 4:05 PM Justin Taraska, National Institutes of Health, USA, Imaging the Nanoscale Structure of Endocytosis and Exocytosis with Light and Electron Microscopy

4:30 - 5:45 PM Ed Chapman, University of Wisconsin, USA, Contrasting the Functions of Synaptagmins 1 and 17

Intrinsically Disordered Proteins

Subgroup Chair: Tanja Mittag, St. Jude Children's Research Hospital

Program Co-Chairs: Hue Sun Chan & Nicolas Fawzi

Baltimore Convention Center Room: Ballroom IV

Business Meeting: 10:30 - 11:30 AM 

Speakers

1:00 - 1:10 PM Tanja Mittag, Opening Remarks

1:10 - 1:40 PM Gary Pielak, University of North Carolina - Chapel Hill, USA, Tardigrade Proteins and Desiccation Tolerance

1:40 - 2:10 PM Jeetain Mittal, Lehigh University, USA, Identifying Sequence-determinants of Protein Liquid-liquid Phase

2:10 - 2:40 PM Joan-Emma Shea, University of California - Santa Barbara, USA, Self-Assembly of the Tau Protein: Fibril Formation and Complex Coacervation

2:40 - 2:45 PM Announcement of Postdoc Awards

2:45 - 3:05 PM Postdoc Award Talk

3:45 - 4:15 PM James Shorter, University of Pennsylvania, USA, Antagonizing Aberrant Phase Separation of RNA-binding Proteins Connected to ALS/FTD

4:15 - 4:45 PM Jean Baum, Rutgers University, USA, Modulating Alpha-synuclein Aggregation through IDP-IDP Interactions

4:45 - 5:05 PM Postdoc Award Talk

5:05 - 5:35 PM Mingjie Zhang, Hong Kong University of Science and Technology, Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity

5:35 - 6:05 PM Wolfgang Peti, University of Arizona, USA, IDPs Enable Substrate Specificity of Protein Phosphatase

6:05 - 6:15 PM Hue Sun Chan & Nicolas Fawzi, Closing Remarks

Mechanobiology

Subgroup Chair: Kristian Franze, Cambridge University, United Kingdom         

Baltimore Convention Center Rooms: 321, 322 and 323

Business Meeting: 5:05 PM - 5:20 PM

Speakers:

9:30 - 9:35 AM Kristian Franze, Opening Remarks

9:35 - 10:05 AM Michael Sheetz, Mechanobiology Institute of Singapore, Normalizing Transformed Cancer Cells with Rigidity Sensing

10:35 - 11:05 AM Jennifer Curtis, Georgia Tech, USA, Physical Role of Hyaluronan Glycocalyx in Cell Adhesion and Migration

11:20 - 11:50 AM Michael Murrell, Yale University, USA, Work and Dissipation in the Cell Cytoskeleton

12:05 - 12:35 PM Manuel Théry, Cytomorphlab Paris, France, Stress fibers and the Cell Cortex Form an Integrated Contractile Network

2:00 - 2:30 PM Clare Waterman, National Institutes of Health, USA, Integrin-mediated Mechano-sensation in Innate Immunity

3:00 - 3:30 PM Matteo Rauzi, Université Côte d'Azur, CNRS, INSERM, France, Cell and Embryo Scale Mechanisms Driving Epithelial Folding

3:45 - 4:15 PM Karen Alim, Max Planck Institute, Germany, Fluid Flows Shaping Morphology

4:30 - 5:00 PM Journal Panel

5:00 - 5:05 PM Closing Remarks

 

 

Membrane Biophysics

Subgroup Chair: Andrew Plested, Leibnize Institute for Molecular Pharmacology, Germany     

Symposia Title: Signal integration in dendrites and other membranes

Baltimore Convention Center Rooms: 314 and 315

Business Meeting: 3:20 PM - 3:50 PM

Speakers 

1:00 - 1:05 PM Opening Remarks

1:05 - 1:35 PM Jeffrey S. Diamond, National Institutes of Health, USA, Compartmentalized Dendritic Signaling in the Retina

1:35 - 2:05 PM Veronica Egger, Regensburg University, Germany, Mechanisms of Local and Global Synaptic Signalling in Olfactory Bulb Granule Cell Dendrite

2:05 - 2:35 PM 

2:35 - 3:05 PM Mala Shah, University College of London, United Kingdom, T-type Ca2+ Channels and Layer II Medial Entorhinal Cortical Stellate Cell Excitability

3:50 - 4:20 PM Bruce Bean, Harvard University, USA, Context and complexity: How Ionic Conductances Interact to Control Neuronal Firing

4:20 - 4:50 PM Marlies Oostland, Princeton University, USA, Neuronal Mechanisms Underlying HCN1-dependent Motor Behavior Deficits

4:50 - 5:20 PM Z. Jimmy Zhou, Yale University, USA, Dendritic Integration and Visual Computation in Retinal Amacrine Cells

5:20 - 5:30 PM Closing Remarks

Membrane Structure & Function

Subgroup Chair: Ilya Leventhal, University of Texas Health Science Center at Houston 

Baltimore Convention Center Room: Ballroom I

Business Meeting: 5:40 PM - 6:00 PM  

Speakers

1:00 - 1:05 PM Ilya Levental, Opening Remarks

1:05 - 1:35 PM Jay Groves, University of California - Berkeley, USA

1:35 - 2:05 PM Claudia Steinem, University of Göttingen, Germany, Pore-spanning Membranes: A Versatile Tool to Investigate Dynamic Processes of Lipid Bilayers

2:05 - 2:35 PM Alex Sodt, National Institutes of Health, USA, Deciphering Nanometer-scale Lipid Structure and Physics to Model Membrane Reshaping

3:30 - 4:00 PM Akihiro Kusumi, Okinawa Institute of Science and Technology Graduate University, Japan, Signal Transduction by Metastable Molecular Complexes: Findings by Single-molecule Tracking

4:00 - 4:30 PM Jenifer Thewalt, Simon Fraser University, Canada, Using Deuterium NMR to Study Sterols & Phospholipids - is it just a phase?

4:30 - 5:00 PM María García-Parajo, The Institute of Photonic Sciences, Spain, Nanophotonic Tools to Resolve Nanoscale Dynamics on Biological Membranes

5:00 - 5:40 PM Dimitrios Stamou, University of Copenhagen, Denmark, Biological Heterogeneity, a Phenotypic Trait that we Harvested to Investigate Membranes and Membrane Proteins

5:40 - 6:00 PM Ilya Levental, Closing Remarks

Presenting Junior Researchers:

2:35 - 2:50 PM Robert Ernst, University of Saarland, Germany, Genetically Encoded Membrane Property Sensors Interrogate Cellular Membranes with Remarkable Sensitivity

3:15 - 3:30 PM Itay Budin, University of California - Berkeley, USA, Cellular Functions for Membrane Viscosity Revealed by Lipid Engineering Efforts

Membrane Transport

Subgroup Chair: Susan Rempe, Sandia National Laboratories

Baltimore Convention Center Room: Ballroom III

Business Meeting: 5:00 PM - 5:30 PM

Speakers:

1:25 - 1:30 PM Susan Rempe, Opening Remarks

1:30 - 2:00 PM Chris Miller, Brandeis University, USA, A Strange Pore to Handle a Strange Anion

2:00 - 2:30 PM Cristina Paulino, Groningen Biomolecular Sciences and Biotechnology Institute, The Netherlands, The KdpFABC Complex: What Happens When a P-type ATPase Hijacks an Ion Channel

2:50 - 3:20 PM Thomas Miller, California Institute of Technology, USA, Dynamics of Co-translational Membrane Integration

3:30 - 4:00 PM Crina Nimigean, Weill Cornell Medical College, USA, Mechanism of Ligand-gating in Potassium Channels

4:20 - 4:50 PM Michael Grabe, University of California - San Francisco, USA, Inhibitor Binding to Human SGLT Sugar Transporters

4:50 - 5:00 PM Susan Rempe, Closing Remarks

 

Molecular Biophysics

Subgroup Chair: Maria Spies, University of Iowa

Symposium Title: Many Layers of Macromolecular Dynamics

Baltimore Convention Center Room: Ballroom II

Business Meeting: 12:15 PM - 12:35 PM

Speakers

10:30 - 10:40 AM Maria Spies, Opening Remarks

10:40 - 11:10 AM Terence Strick, Institut Jacques Monod, University Paris Diderot, France, Real-Time Monitoring of Multivalent DNA Repair Complexes in Action

11:10 - 11:35 AM Alejandro Martin-Gonzalez, National Center for Biotechnology (CNB, Madrid), Spain, AFM shows that Human CtIP Forms a Tetrameric Dumbbell-shaped Particle which Binds and Bridges DNA Ends

11:35 AM - 12:05 PM Claire Wyman, Erasmus University Medical Center, The Netherlands, Dynamic Proteins and Interactions Driving Homologous Recombination: A BRCA2 Centric View

12:35 - 1:05 PM Catherine Musselman, University of Iowa, USA, The Effect of Nucleosome Conformation on Histone Tail Binding and Specificity

1:05 - 1:30 PM Sonja Schmid, Delft University of Technology, The Netherlands, High Bandwidth Sensing of Single Protein Dynamics Using Nanopores and DNA Origami

1:30 - 2:00 PM Sharonda LeBlanc, UNC Chapel Hill, USA, Investigating the Function of MutL Conformational Changes in Mismatch Repair using smFRET

2:00 - 2:30 PM Thomas Perkins, University of Colorado, USA, Probing and Reconstructing Free-energy Landscapes of Diverse Bimolecular Systems by AFM

2:30 - 3:00 PM Maria Spies, Closing Remarks

Motility & Cytoskeleton

Subgroup Co-Chairs: William Hancock, Pennsylvania State University and Neil Kad, University of Kent, United Kingdom

Baltimore Convention Center Rooms: 318, 319 and 320

Business Meeting: 4:35 PM - 5:15 PM

Speakers 

1:00 - 1:05 PM William Hancock and Neil Kad, Opening Remarks

1:05 - 1:30 PM Magdalena Bezanilla, Dartmouth College, USA, Cytoskeletal Dynamics During Polarized Growth

1:30 - 1:55 PM Ethan Garner, Harvard University, USA, Single Molecule Approaches to Understanding Bacterial Width and Growt

2:00 - 2:25 PM Jonathan Bird, University of Florida, USA, Sensing Sound over a Lifetime: How Myosin Motors Continually Shape the Stereocilia Cytoskeleton

3:00 - 3:25 PM Ken'ya Furuta, National Institute of Information and Communications Technology, Japan, Re-design of Linear Molecular Motors

3:25 - 3:50 PM Erik Schäffer, University of Tübingen, Germany, Novel Optical Tweezers Probes: How Kinesin Motors Get to the Microtubule End

3:55 - 4:20 PM Pasquale Bianco, University of Florence, Italy, A Myosin II Nanomachine Mimicking the Striated Muscle

5:15 - 6:15 PM Michael Geeves, University of Kent, United Kingdom, Lessons from the Actin-myosin II Family; Docking, Mechanochemistry and Myopathies

Nanoscale Biophysics

Subgroup Co-Chairs: Keir Neuman, National Institutes of Health and Ozgur Sahin, Columbia University

Baltimore Convention Center Rooms: 316 and 317

Business Meeting: 5:20 PM - 6:00 PM

Speakers 

12:30 - 12:35 PM Keir Neuman, Opening Remarks

12:35 - 1:05 PM Ibrahim Cissé, MIT, USA, Super-resolution Imaging of Transcription in Live Mammalian Cells

1:05 - 1:35 PM Marie-Eve Aubin-Tam, Delft University of Technology, The Netherlands, Nanodiscs and Free-standing Bilayers for Single-molecule Studies at the Lipid Membrane

1:35 - 2:05 PM Bart Hoogenboom, University College London and London Centre of Nanotechnology, United Kingdom, Visualising Self-Assembly of Pore Forming Proteins on Their Target Membranes

2:05 - 2:35 PM Suliana Manley, Ecole Polytechnique Fédérale De Lausanne, Switzerland, High-throughput Super-resolution Microscopy for Revealing Molecular Architecture

3:50 - 4:20 PM Sabrina Leslie, McGill University, Canada, Single-molecule Imaging of Structure-mediated Interactions in DNA Molecules under Cell-like Condition

4:20 - 4:50 PM Philipp Kukura, Oxford University, United Kingdom, Weighing Single Molecules with Light

4:50 - 5:20 PM Peng Yin,  Harvard Medical School, USA, Biomolecular Analysis with DNA Probe

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