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Sunday, June 7, 2020

4:00 PM - 6:00 PM
Registration

6:00 PM - 7:00 PM
Welcome Reception

7:00 PM - 8:00 PM
Dinner

8:00 PM - 8:15 PM
Opening Remarks
Merritt Maduke, Stanford University and Linda Columbus, University of Virginia, Conference Organizers

8:15 PM - 9:15 PM
Keynote Address
Patricia Bassereau, Institut Curie, France
Proteins Can Shape Membranes, and Membrane Shape can influence Proteins' Function

9:15 PM - 9:45 PM
Flash Talks

Monday, June 8, 2020

7:00 AM - 8:30 AM
Breakfast

Session I: Mechanotransduction in the Membrane
Miriam Goodman, Stanford University, Chair

9:00 AM - 9:30 AM
Miriam Goodman, Stanford University
Deciphering Touch Sensation at the Membrane-Matrix Interface

9:30 AM - 10:00 AM
Xin Liang, Tsinghua University, China
Molecular Architecture of the Mechanoreceptive Organelle in Fly Campaniform Mechanoreceptors

10:00 AM - 10:30 AM
Medha Pathak, University of California, Irvine
PIEZO1 on the Move

10:30 AM - 11:00 AM
Coffee Break and Group Photo

11:00 AM - 11:30 AM
Bailong Xiao, Tsinghua University, China
Structure and Mechanogating of the PIEZO Channel

11:30 AM - 11:45 AM
Short Talk 1 *

11:45 AM - 12:00 PM
Short Talk 2 *

12:00 PM - 1:00 PM
Special-topic hosted Lunch Table
Teaching and Mentoring: inclusive practices (Linda Columbus)

1:00 PM - 2:30 PM
Panel Discussion: Challenges of Diversity and Inclusion in Science and Developing Action-Plans for Overcoming Them
Panelists: Linda Columbus, Karen Fleming, Miriam Goodman, Carlos Villalba-Galea

2:30 PM - 4:00 PM
Free Time

4:00 PM - 6:00 PM
Poster Session I

6:00 PM - 7:00 PM
Dinner

Session II: Membrane Organization
Sergio Grinstein, University of Toronto, Canada, Chair

7:00 PM - 7:30 PM
Sergio Grinstein, University of Toronto, Canada
Phosphoinositide-Gated Ion Fluxes Regulate Membrane Curvature and Traffic

7:30 PM - 8:00 PM
Susan Daniel, Cornell University
Reconstitution of Native Membranes on Bioelectronic Devices with Dual Electrical and Optical Monitoring of Transmembrane Protein Function

8:00 PM PM - 8:30 PM
Syma Khalid, University of Southampton, United Kingdom
The Cell Envelope of Gram-Negative Bacteria: Deciphering the Complexity

8:30 PM PM - 8:45 PM
Short Talk 3 *

8:45 PM PM - 9:00 PM
Short Talk 4 *

9:00 PM - 11:00 PM
Mixer

Tuesday, June 9, 2020

7:00 AM - 8:30 AM
Breakfast

Session III: Signaling through the Membrane
Lynmarie Thompson, University of Massachusetts, Amherst, Chair

9:00 AM - 9:30 AM
Lynmarie Thompson, University of Massachusetts, Amherst
NMR and Hydrogen Exchange Studies of Chemoreceptor Complexes Suggest Signaling Occurs Via Stabilization of a Disordered Domain

9:30 AM - 10:00 AM
Anne Carlson, University of Pittsburgh
PIP2 Potentiates the Calcium-Activated Chloride Channel TMEM16A in Xenopus Laevis Oocytes

10:00 AM - 10:30 AM
Yulong Li, Peking University, China
Spying on Dopamine Modulation by Develping Next-Generation Grab Sensors

10:30 AM - 10:45 AM
Coffee Break

10:45 AM - 11:15 AM
William Kobertz, University of Massachusetts Medical School
Seeing What’s Out There: Fluorescent Visualization of Cellular Fluxes

11:15 AM - 11:45 AM
Carlos Villalba-Galea, University of the Pacific
Regulation of KV7 Channels Deactivation

11:45 AM - 12:00 PM
Short Talk 5 *

12:00 PM - 1:00 PM
Special-topic hosted Lunch Table
Careers: Being a Professor at a Teaching University (Carlitos Villalba-Galea)

1:00 PM - 2:30 PM
Workshop: Tips for Successful NIH Grant Proposals
Zhongzen Nie, NIH, NIGMS

2:30 PM - 4:00 PM
Free Time

4:00 PM - 6:00 PM
Poster Session II

6:00 PM - 7:00 PM
Dinner

Session IV: Membrane Shape
Dimitrios Stamou, University of Copenhagen, Denmark, Chair

7:00 PM - 7:30 PM
Dimitrios Stamou, University of Copenhagen, Denmark
Membrane Curvature as a Pluripotent Regulator of GPCR Signaling

7:30 PM - 8:00 PM
Rumiana Dimova, Max Planck Institute of Colloids and Interfaces, Germany
Curving in or Out: Membrane Remodeling and Spontaneous Curvature Generation by Ions, (Sugar) Lipids, Polymers and Proteins

8:00 PM PM - 8:30 PM
Jeet Kalia, Indian Institute of Science Education and Research Bhopal, India
Employing the Double Knot Toxin-TRPV1 Ion Channel Complex as a Model System to Interrogate the Roles of Protein-Membrane Interactions in Protein Function

8:30 PM PM - 8:45 PM
Short Talk 6 *

8:45 PM PM - 9:00 PM
Short Talk 7 *

9:00 PM - 11:00 PM
Mixer

Wednesday, June 10, 2020

7:00 AM - 8:30 AM
Breakfast

Session V: Ion Channels and Transporters
Joseph Mindell, NINDS, NIH, Chair

9:00 AM - 9:30 AM
Joseph Mindell, NINDS, NIH
Insights into Regulation of Lysosomal pH By The Chloride Transporter ClC-7: Role of Signaling Lipids

9:30 AM - 10:00 AM
Richard Hite, Sloan Kettering Institute
Gating and Selectivity Mechanisms for the Non-Canonical Lysosomal K+ Channel TMEM175

10:00 AM - 10:30 AM
Randy Stockbridge, University of Michigan
Structural Basis for Substrate Specificity in the Small Multidrug Resistance Family of Transporters

10:30 AM - 10:45 AM
Coffee Break

10:45 AM - 11:15 AM
Lucy Forrest, NINDS, NIH
Mechanism of Osmotic Stress Detection by a Membrane Transport Protein

11:15 AM - 11:30 AM
Short Talk 8 *

11:30 AM - 11:45 AM
Short Talk 9 *

11:45 AM - 12:00 PM
Short Talk 10 *

12:00 PM - 1:00 PM
Special-topic hosted Lunch Table
Careers: Research in Biotech (Jian Payandeh, Genentech)

1:00 PM - 2:30 PM
Panel Discussion: Establishing Expectations and Benchmarks in Collaborations Between Experiment and Computation
Panelists: Linda Columbus, Lucy Forrest, Syma Khalid, Joseph Mindell, and Janice Robertson

2:30 PM - 4:00 PM
Free Time

4:00 PM - 6:00 PM
Poster Session III

6:00 PM - 6:30 PM
Dinner

6:30 PM - 7:00 PM
Business Meeting

Session VI: Membrane Protein Dynamics
Linda Columbus, University of Virginia, Chair

7:00 PM - 7:30 PM
Linda Columbus, University of Virginia
Impact of Lipid-Membrane Protein Interactions on Membrane Protein Structure and Dynamics

7:30 PM - 8:00 PM
Hassane Mchaourab, Vanderbilt University Medical Center
Ligand Dependent Alternating Access of MATE Transporters

8:00 PM PM - 8:30 PM
Gregory Voth, University of Chicago
Membrane Remodeling by Proteins: Insights and Surprises from Multiscale Computer Simulation

8:30 PM PM - 8:45 PM
Short Talk 11 *

8:45 PM PM - 9:00 PM
Short Talk 12 *

9:00 PM - 11:00 PM
Mixer

Thursday, June 11, 2020

7:00 AM - 8:30 AM
Breakfast

Session VII: Membrane Protein Folding
Karen Fleming, Johns Hopkins University, Chair

9:00 AM - 9:30 AM
Karen Fleming, Johns Hopkins University
From Chaperones to the Membrane with a BAM!

9:30 AM - 10:00 AM
Jonathan Schlebach, Indiana University Bloomington
Stimulation of Programmed Ribosomal Frameshipting by Contranslational Folding and Misfolding

10:00 AM - 10:30 AM
Ismael Mingarro, University of Valencia, Spain
Folding of Helices inside the Robosome Exit Tunnel

10:30 AM - 10:45 AM
Coffee Break

10:45 AM - 11:15 AM
Joanna Slusky, University of Kansas
Disabling Antibiotic Efflux in the Outer Membrane

11:15 AM - 11:30 AM
Short Talk 13 *

11:30 AM - 11:45 AM
Short Talk 14 *

11:45 AM - 12:00 PM
Short Talk 15 *

12:00 PM - 1:00 PM
Special-topic hosted Lunch Table
Publishing: Thoughts from the Perspective of Academic Editors (Dimitrios Stamous, BJ editor; Merritt Maduke, JGP editor)

1:00 PM - 4:00 PM
Free Time

4:00 PM - 6:00 PM
Poster Session IV

6:00 PM - 7:00 PM
Dinner

Session VIII: Membrane Fusion and Exocytosis
Kelly Lee, University of Washington

7:00 PM - 7:30 PM
Kelly Lee, University of Washington
Cryo-Electron Tomography as a Tool for Understanding Protein-Mediated Membrane Remodeling

7:30 PM - 8:00 PM
TBD
 

8:00 PM PM - 8:30 PM
Anna Akhmanova, Utrecht University, The Netherlands
Molecular Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic Microtubules

8:30 PM PM - 8:45 PM
Short Talk 16 *

8:45 PM PM - 9:00 PM
Short Talk 17 *

9:00 PM - 11:00 PM
Closing Mixer

Friday, June 12, 2020

7:00 AM - 8:30 AM
Breakfast and Departure
 

* Short Talks selected from among submitted abstracts