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Sunday, March 31, 2019

16:00 – 19:30
Registration/Information

19:30 – 21:00
Opening Dinner
 

Monday, April 1, 2019

8:30 – 18:35
Registration/Information

8:45 – 9:00
Opening Remarks
Tamar Schlick, New York University, USA

Session I
Tamar Schlick, New York University, USA, Chair

9:00 – 9:30
Mair Churchill, University of Colorado, Denver, USA
Histone Trafficking During Chromatin Replication

9:30 – 10:00
Ivet Bahar, University of Pittsburgh, USA
Chromatin Dynamicsstudied by the Gaussian Network Model: Short- and Long-Range Couplings Between Geneloci

10:00 – 10:30
Anna Panchenko, NCBI, NIH, USA
Integrating in Silico and in Vitro Approaches to Characterize Nucleosome Structure and Dynamics with High Precision

10:30 – 11:00
Coffee Break

Session II
Helmut Schiessel, Leiden University, the Netherlands, Chair

11:00 – 11:30
Garegin Papoian, University of Maryland, USA
Structural Plasticity of Histone Oligomers and Their Interactions with Chaperones and Other Regulators

11:30 – 11:50
Alexey Onufriev, Virginia Tech, USA*
DNA Accessibility Control in the Nucleosome: Insights from Physics

11:50 – 12:10
Jürgen Walther, IRB Barcelona, Spain*
Understanding Gene Regulation through the 3D Structure of Chromatin and Chromosomes

12:30 – 13:30
Lunch Break

13:30 – 17:00
Networking

Session III
Lars Nordenskiöld, Nanyang Technological University, Singapore, Chair

17:00 – 17:30
Helmut Schiessel, Leiden University, the Netherlands
The Mechanical Genome

17:30 – 18:35
Poster Pitches

19:00 – 19:30
Welcome Reception

19:30 – 21:00
Dinner

21:00 – 22:00
Poster Session I

 

Tuesday, April 2, 2019

8:30 – 19:05
Registration/Information

Session IV
Tom Bishop, Louisiana Tech University, USA Chair

9:00 – 9:30
Mark Ellisman, University of California, San Diego, USA
Imaging Local and Global Chromatin Structure as a 3D Continuum within the Nucleus: Progress and Future Strategies

9:30 – 10:00
Ariel Kaplan, Technion - Israel Institute of Technology, Israel
Nucleosome Diffusion and Gene Expression Regulation: Insights from Single Molecule Studies

10:00 – 10:30
Tom Bishop, Louisiana Tech University, USA
TBD

10:30 – 11:00
Coffee Break

Session V
Jie Yan, Mechanobiology Institute, National University of Singapore, Singapore, Chair

11:00 – 11:20
Madhura De, Heidelberg University, Germany*
Positioning the Linker Histone on a Chromatosome: What Role Does the DNA Play?

11:20 – 11:40
Anat Galis Vivante, Bar Ilan University, Israel*
Chromatin Dynamics Governed by a Set of Nuclear Structural Proteins

11:40 – 12:00
Hugo van Ingen, Utrecht University, the Netherlands*
Capturing Interactions to the Nucleosome Acidic Patch by Multi-Scale NMR

12:30 – 13:30
Lunch Break

13:30 – 17:40
Networking

Session VI
Andrzej Stasiak, University of Lausanne, the Netherlands, Chair

17:45 – 18:05
Catherine Royer, Rensselaer Polytechnic Institute, USA*
Superresolution Imaging of the Start Transcription Factors

18:05 – 19:05
Poster Pitches

19:30 – 21:00
Dinner

21:00 – 22:00
Poster Session II

 

Wednesday, April 3, 2019

8:30 – 19:05
Registration/Information

Session VII
Garegin Papoian, University of Maryland, USA, Chair

9:00 – 9:30
Hitoshi Kurumizaka, University of Tokyo, Japan
Structural Studies of Chromatin: Toward Understanding the Regulation of Genomic DNA

9:30 – 10:00
Jie Yan, Mechanobiology Institute, National University of Singapore, Singapore
Transfer-Matrix Calculation of the Effects of Physical Constraints Applied to DNA on DNA-Protein Interactions

10:00 – 10:30
Tamar Schlick, New York University, USA
TBD

10:30 – 11:00
Coffee Break

Session VIII
Hitoshi Kurumizaka, University of Tokyo, Japan, Chair

11:00 – 11:20
Pablo D. Dans Puiggròs, IRB Barcelona, Spain*
Understanding Gene Regulation Through the 3d Structure of Chromatin and Chromosomes

11:20 – 11:40
Joshua Moller, University of Chicago, USA*
Unveiling Chromatin Fiber Condensation Through Many-Body Nucleosome Interactions

11:40 – 12:00
Marina Katava, University of Texas at Austin, USA*
Unveiling Chromatin Fiber Condensation Through Many-Body Nucleosome Interactions

12:30 – 13:30
Lunch Break

13:30 – 17:45
Networking

Session IX
Mair Churchill, University of Colorado, Denver, USA, Chair

17:45 – 18:15
Lars Nordenskiöld, Nanyang Technological University, Singapore
Structure and Dynamics of the Telomeric Nucleosome and Chromatin

18:15 – 18:35
Quinn MacPherson, Stanford University, USA*
Heterochromatin and the Nuclear Periphery: Specificity via Density

18:35 – 19:05
Toshio Tsukiyama, Fred Hutchinson Cancer Research Center, USA
Mechanisms and Functions of Chromatin Condensation in Quiescent Yeast Cells

19:30 – 21:00
Dinner

21:00 – 22:00
Poster Session III

 

Thursday, April 4, 2019

8:30 – 19:05
Registration/Information

Session X
G.V. Shivashankar, Mechanobiology Institute, National University of Singapore, Singapore , Chair

9:00 – 9:30
Amartya Sanyal, Nanyang Technological University, Singapore
Connecting Genomic and Non-Genomic Mechanisms of Cancer Drug Resistance

9:30 – 10:00
Angelo Rosa, International School for Advanced Studies, Italy
From Chromosome Territories to Ring Polymers: Physical Properties of Untangled Polymer Melts

10:00 – 10:30
Alexandra Zidovska, New York University, USA
The "Self-Stirred" Genome: Bulk and Surface Dynamics of the Chromatin Globule

10:30 – 11:00
Coffee Break

Session XI
Erez Lieberman-Aiden, Baylor College of Medicine, USA, Chair

11:00 – 11:20
Artemi Bendandi, University of Genoa, Italy*
Mesoscale Bottom-Up Approach to the Study of Chromatin Topological Conformations: From the Nucleosome to 1Mbps

11:20 – 11:40
Soya Shinkai, RIKEN, Center for Biosystems Dynamics Research, Japan*
Deciphering Hi-C Data into Polymer Dynamics

11:40 – 12:00
Michele Di Pierro, Rice University, USA*
The Three-Dimensional Architecture of the Human Genome: It’s Nuclear Physics!

12:30 – 13:30
Lunch Break

13:30 – 17:45
Networking

Session XII
Amartya Sanyal, Nanyang Technological University, Singapore, Chair

17:45 – 18:15
G.V. Shivashankar, Mechanobiology Institute, National University of Singapore, Singapore
Mechanical Control of Chromosome Organization and Gene Expression

18:15 – 18:45
Erez Lieberman-Aiden, Baylor College of Medicine, USA
A 3D Code in the Human Genome

18:45 – 19:05
Anne Shim, Northwestern University, USA*
The Crowded Nanoenvironment Influences Gene Expression

19:30 – 21:00
Dinner

21:00 – 22:00
Poster Session IV

 

Friday, April 5, 2019

8:30 – 13:30
Information

Session XIII
John van Noort, Leiden University, the Netherlands, Chair

9:00 – 9:30
Andrzej Stasiak, University of Lausanne, the Netherlands
TADs and chromatin supercoiling

9:30 – 10:00
Vlad Cojocaru, Max-Planck Institute for Molecular Biomedicine, Germany
How Do DNA-Binding Proteins Interpret and Modify Nucleosome Dynamics?

10:00 – 10:30
Coffee Break

Session XIV
Alexandra Zidovska, New York University, USA, Chair

10:30 – 11:00
John van Noort, Leiden University, the Netherlands
Chromatin Higher Order Folding in Irregular Fibers: A Critical Role of Linker DNA

11:00 – 11:30
Wilma Olson, Rutgers University, USA
Contributions of Nucleosome Architecture to Long-Range Communication on Chromatin

11:30 – 12:00
Closing Remarks and Biophysical Journal Poster Awards
Tom Bishop, Louisiana Tech University, USA

12:30 – 13:30
Lunch

*Short talks selected from among submitted abstracts