The molecular processes that drive and regulate the flow of information from genes to proteins—i.e., the central dogma of molecular biology—have been extensively studied using traditional biochemical and molecular tools. However, thanks to the advent of single-molecule manipulation and nanoscale visualization techniques, many unknown biophysical aspects of these processes have been unveiled.
This meeting aims to cover recent discoveries produced by single-molecule approaches in the biophysics of replication, transcription, protein synthesis, chaperone-mediated protein folding/degradation, and molecular motors. Additional topics include the latest developments in single molecule instrumentation and nanoscale visualization, steered molecular dynamics simulations, and single-molecule applications for the study of pathogens and infectious diseases.