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2002
biophysical discussions study book
Saturday AM
9:00 AM to 12:00 NOON
Session I: The State of
Structural Biology of Large Structures
Moderator Helen Saibil,
Birkbeck College
The
Power of Electron Cryomicroscopy
Richard Henderson, MRC–Laboratory
of Molecular Biology
The
Ribosome–A Molecular Machine in Motion
Joachim Frank, SUNY, Albany
Biochemical
Basis for X-Ray Crystallography of the Ribosome
Jamie Cate, University of
California, Berkeley
Saturday PM
4:30 PM to 6:00
PM
Posters
7:30 PM to 10:30 PM
Session II: Extending X-Ray
Crystallography to Ever Larger Structures
Moderator Keith Hodgson,
Stanford University
Can
We Routinely Collect Useful Data from Micro-Crystals?
Andrew Thompson, EMBL, Grenoble
Future
X-Ray Sources (tentative)
Janos Hajdu, Upsala University
The
Phase Problem: Does Size Matter?
Randy Read, University of
Cambridge
Sunday AM
9:00 AM to 12:00 NOON
Session III: What Does the
Future Hold for Electron Cryomicroscopy?
Moderator Bob Glaeser, University
of California, Berkeley
Single
Particles Always Fit the Mold
Niko Grigorieff, Brandeis
University
Tubulin
and Microtubule Structures - The Best of Electron Crystallography and Single
Particle Approaches
Ken Downing, Lawrence Berkeley
Laboratory
Electron
Tomography: Towards Visualizing Macromolecular Assemblies Inside Cells
Wolfgang Baumeister,Max-Planck
Institute, Martinsried
Polymorphism,
Can We Detect It? Can We Use It? Can We Control It? Examples from
Actin and Nucleoprotein Complexes
Edward Egelman, University
of Virginia Health Science Center
Sunday PM
4:30 PM to 6:00
PM
Posters
7:30 PM to 10:30 PM
Session IV: Can Hybrid Methods
Provide Credible Atomic Models?
Moderator Eva Nogales, University
of California, Berkeley
Atomic
Model of the Cell: Docking in a Ttomographic Environment
Niels Volkmann, Burnham
Institute
Reconciling
Shape with Structure: Morphometric Strategies for Multi-Resolution Flexing
Willy Wriggers, Scripps
Research Institute
Combining
electron microscopic with x-ray crystallographic structures
Michael Rossman, Purdue
University
Addendum
Monday AM
9:00 AM to 12:00 NOON
Session IV: Computational
Methods
Moderator Axel Brunger,
Stanford University
Modeling
of Molecular Assemblies by Satisfaction of Constraints
Andrej Sali, Rockefeller
University
Probing
the Structural and Energetic Basis of Protein-Protein Interactions
Barry Honig, Columbia University
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