Daily Schedule

Tuesday, October 10, 2017

9:30 AM - 7:00 PM
Registration/ Information

10:35 AM – 10:45 AM
Opening Remarks
Tamara Rosenbaum, National Autonomous University of Mexico

Session I: Ligand-gated Channels
Eitan Reuveny, Weizmann Institute, Israel, Chair

10:45 AM - 11:10 AM
Lucia Sivilotti, University College London, United Kingdom
The Activation of Glycine Channels: A Single-Channel Perspective

11:10 AM - 11:35 AM
Cecilia Bouzat, Instituto de Investigaciones Bioquímicas de Bahía Blanca, Argentina
α7 Nicotinic Receptors at the Single-Channel Level

11:35 AM - 12:00 PM
Vasanthi Jayaraman, University of Texas Medical School at Houston, USA
Glutamate Receptor Dynamics

12:00 PM - 1:30 PM
Lunch (on own)

Session II: Ion Channels in Physiology
László Csanády, Sammelweis University, Hungary, Chair

1:30 PM - 1:55 PM
Polina Lishko, University of California, Berkeley, USA
Ion Channels and Sperm Physiology

1:55 PM - 2:15 PM
Andrea Brüggemann, Nanion Technologies GmbH, Germany *
News and Views on Cardiac Safety

2:15 PM - 2:40 PM
Uhtaek Oh, Seoul National University, South Korea
Physiological Implications of Anoctamin 1, a Calcium-activated Chloride Channel

2:40 PM - 3:05 PM
Andrea Meredith, University of Maryland, USA
Molecular Mechanisms of Circadian Variation in BK Channel Properties

3:05 PM - 3:30 PM
Thomas Voets, University of Leuven, Belgium
TRP Channels in Noxious Heat Sensing and Pain

3:30 PM - 5:30 PM
Poster Session I

Session III: Keynote Talk
Leon D. Islas, National Autonomous University of Mexico, Chair

5:40 PM - 6:30 PM
Frederick Sigworth, Yale University, USA
Cryo-EM Imaging of a Voltage-gated Channel with Membrane Potential Applied.

7:00 PM
Welcome Dinner

Wednesday, October 11, 2017

8:30 AM - 7:00 PM

Session IV: Mechanically-activated Ion Channels
William Zagotta, University of Washington, USA, Chair

9:00 AM - 9:25 AM
Jorg Grandl, Duke University, USA
Magnetic Force Probing of Mechanically-activated Piezo Ion Channels

9:25 AM - 9:45 AM
Elizabeth Heath-Heckman, University of California, Berkeley, USA*
Using Leeches to Discover Novel Ion Channels Involved in Mechanotransduction

9:45 AM - 10:10 AM
Miriam Goodman, Stanford University, USA
Genetics and Physics of in Vivo Mechanical Activation of Ion Channels

10:10 AM - 10:30 AM
H. Peter Lu, Bowling Green University, USA*
Revealing NMDA Receptor Hidden Conformational Open States that Block Electric Current under Agonist Activation in Living Cells by a Novel Single-Molecule Patch-clamp Fret Superresolution Microscopy

10:30 AM - 10:50 AM
Coffee Break

Session V: Modulation of Ion Channels
Sharona Gordon, University of Washington, USA, Chair

10:50 AM - 11:15 AM
Eitan Reuveny, Weizmann Institute, Israel
Regulation of Ion Channel Activity.

11:15 AM -  11:40 AM
Ramón Latorre, University of Valparaiso, Chile
Modulation of the BK Channel by Auxiliary Subunits

11:40 AM - 01:30 PM
Lunch (on own)

Session VI: Methods for the Study of Ion Channels I
Andrea Meredith, University of Maryland, USA, Chair

1:30 PM - 1:55 PM
Werner Treptow, Universidade de Brasilia, Brazil
Binding of General Anesthetics to Ion Channels

1:55 PM- 2:20 PM
Justin Taraska, NIH, USA
Imaging the Nanometer-scale Structure of the Plasma Membrane with Correlative Superresolution Light and Electron Microscopy

2:20 PM - 2:45 PM
William Zagotta, University of Washington, USA
Molecular Mechanisms of Regulation of Ion Channels by Intracellular Domains

2:45 PM - 3:05 PM
Bruce Cohen, Lawrence Berkeley National Laboratory, USA*
Characterization of Dynamic Kv Channel-Toxin Structures with Voltage Clamp Spectroscopy

3:05 PM - 5:05 PM
Poster Session II

Session VII: Methods for the Study of Ion Channels II
Justin Taraska, NIH, USA, Chair

5:15 PM - 5:40 PM
Richard Aldrich, University of Texas, Austin, USA
Calcium, Calmodulin, and Potassium Channels

5:40 PM - 6:05 PM
Francisco Bezanilla, University of Chicago, USA
Optical Approaches in Studies of Excitability 

6:05 PM - 6:30 PM
Ivana Nikic, Werner Reichart Centre for Integrative Neuroscience, Germany
Minimal Tags for Live-Cell Protein Labelling and Superresolution microscopy

6:30 PM - 6:50 PM
Corianne Van den Akker, Stanford University, USA *
Combining Electrical and Optical Measurements on Voltage-gated Potassium Channels

6:50 PM - 7:10 PM
Simon Scheuring, Weill Cornell Medicine, USA *
High-speed Atomic Force Microscopy (HS-AFM): A New Tool for the Direct Study of Conformational Changes in Gated Ion Channels

Thursday, October 12, 2017

Morning Free

12:00 PM - 7:00 PM

Session VIII: Mechanisms I
Miriam Goodman, Stanford University, USA, Chair

1:30 PM - 1:55 PM
Feng Qin, SUNY, USA
Temperature-dependent Gating in Ion Channels

1:55 PM - 2:15 PM
Andrés Jara-Oseguera, NIH, USA *
The Role of the Selectivity Filter in Gating of the TRPV1 Channel.

2:15 PM - 2:40 PM
László Csanády, Sammelweis University, Hungary
Asymmetric Movements Reveal Distinct Roles of CFTR's Two Nucleotide Binding Sites

2:40 PM - 3:05 PM
Sharona Gordon, University of Washington, USA
Dynamic Regulation of TRPV1 Ion Channels

3:05 PM - 5:05 PM
Poster Session III

Session IX: Structure Approaches to Membrane Proteins
Richard Aldrich, University of Texas, Austin, USA, Chair

5:15 PM - 5:40 PM
Montserrat Samso, Virginia Commonwealth University, USA
Ryanodine Receptors: Cross Talk between Allosteric and Ligand-binding Domains

5:40 PM- 6:00 PM
Taylor Hughes, Case Western Reserve University, USA *
Structural Basis of the TRPV5 Channel Modulation Revealed by Cryo-EM

6:00 PM - 6:25 PM
Nancy Carrasco, Yale University, USA
Structure of Membrane Transporters

6:25 PM - 6:50 PM
Crina Nimigean, Cornell University, USA
Gating and Ligand Modulation in Potassium Channels

6:50 PM - 7:10 PM
Michael Grabe, University of California, San Francisco, USA *
Atomistic Insight into Lipid Translocation by a TMEM16 Scramblase

Friday, October 13, 2017

8:30 AM - 12:00 PM

Session X: Lipids and Membrane Proteins
Crina Nimigean, Cornell University, USA, Chair

9:00 AM - 9:25 AM
Andrea Alessandrini, CNR-Institute of Nanoscience, Italy
Lipid-protein Interactions in Model Membranes

9:25 AM - 9:50 AM
Toshinori Hoshi, University of Pennsylvania, USA
Dietary Oils and BK Channels

9:50 AM - 10:15 AM
Raimund Dutzler, University of Zurich, Switzerland
Mechanistic Relationships in the TMEM16 Family of Calcium-activated Chloride Channels and Lipid Scramblases

10:15 AM - 10:35 AM
Coffee Break

Session XI: Mechanisms II
Andrés Jara-Oseguera, NIH, USA, Chair

10:35 AM - 11:00 AM
Yasushi Okamura, Osaka University, Japan
Coupling Mechanisms of Voltage-sensing Phosphatase

11:00 AM - 11:20 AM
Paul DeCaen, Northwestern University, USA *
Defining ADPKD-2 Mutation Effects on Ciliary PKD2 Ion Channels.

11:20 AM - 11:35 AM
Closing Remarks and Biophysical Journal Poster Awards
Richard Aldrich, University of Texas, Austin, USA

*Contributed talks selected from among submitted abstracts