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Jan Hoek, Thomas Jefferson University, Subgroup Co-Chair
György Hajnóczky, Thomas Jefferson University, Subgroup Co-Chair

Bioenergetics Subgroup 2015 Symposium
Saturday, February 7, 2015
Baltimore, Maryland

Morning Symposium: The Mitochondrial Genome
Program Chair: Brett Kaufman, University of Pennsylvania

9:00 AM 

Carlos Moraes, University of Miami
Selective Targeting of MtDNA Sequences and Aplications to Therapy

9:30 AM     

Craig Cameron, Pennsylvania State University
New Paradigms for Regulation of Human Mitochondrial Transcription

10:00 AM 

Phillip West, Yale University
Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

10:30 AM 

Break

11:00 AM 

Yves Pommier, NIH
MtDNA Topoisomerases

11:30 AM 

Brett Kaufman, University of Pennsylvania
New Insights into the Causes of Mitochondrial Genome Instability


Afternoon Symposium: Mitochondrial Outer Membrane Transport Systems: Structure, Properties, and Physiological Implications
Program Chairs: Marco Colombini, University of Maryland; John J. Lemasters, Medical University of South Carolina

1:45 PM         

Shelagh Ferguson-Miller, Michigan State University
High Resolution Crystal Structures of Translocator Protein 18 kDa (TSPO)
Reveal Ligand Binding Sites and Effects of a Human Single Polymorphism
 

2:15 PM 

Vassilios Papadopoulos, McGill University
Translocator Protein in Mitochondrial Cholesterol Transport and the Pharmacology of Steroidogenesis

2:45 PM 

Marco Colombini, University of Maryland
Bax Channels: Cooperativity and Voltage Gating

3:15 PM 

Break

3:45 PM 

 Jeff Abramson, University of California, Los Angeles
Structure-guided Simulations Illuminate the Mechanism of ATP Transport Through VDAC1

4:15 PM 

John J. Lemasters, Medical University of South Carolina
VDAC and Regulation of Mitochondrial Metabolism 

4:45 PM 

General Discussion

5:00 PM 

Subgroup Business Meeting

7:00 PM 

Subgroup Dinner