Scientific Program

Tuesday, November 9, 2010

Morning Session
Molecular Aspects of Actin

Roberto Dominguez, University of Pennsylvania
Molecular Mechanisms of Actin Filament Nucleation

Edward Egelman, University of Virginia
Plasticity and Conservation in Filaments Formed by Actin and Actin-like Proteins

Shin’ichi Ishiwata, Waseda University, Japan
Polymerization, Strain and Function of Actin as a Substrate for Myosin Motors

Jean-Francois Joanny, Curie Institute, CNRS
Role of ATP Hydrolysis in the Treadmilling of Actin Filaments

Robert Robinson, Institute of Molecular and Cell Biology, Singapore
Capping and Uncapping Actin Filaments

Afternoon Session
Molecular Aspects of Actin

Michael Sheetz, Columbia University
Actin Dependant Stretching of Talin In Vivo

Gregory Voth, University of Chicago
A Molecular Scale Perspective on Actin Filament Structure and Dynamics

Jie Yan, National University of Singapore
Magnetic Tweezers Studies of Stretching and Refolding the Actin-Binding Protein Filamin A

Toshio Yanagida, Osaka University, Japan
Actin Dynamic Polymorphism Observed by Single Molecule FRET

 Wednesday, November 10, 2010

Morning Session
Nuclear Actin and Nuclear Mechanics

Brian Burke, Institute of Medical Biology, Singapore
Meiotic Recombination: LINCs to the Cytoskeleton

Primal de Lanerolle, University of Illinois, Chicago
Actin Based Motors in the Nucleus: What They Are and What They Do

Ohad Medalia, The Ben-Gurion University, Israel
From the Nuclear Periphery to Cell Adhesion by Cryo-Electron Tomography

G.V. Shivashanker, National University of Singapore
Mechanosignaling to the Cell Nucleus & Gene Regulation

Maria Vartiainen, University of Helsinki, Finland
Dynamics of Nuclear Actin

Denis Wirtz, Johns Hopkins University
The Perinuclear Actin Cap in Health and Disease

Afternoon Session
Actin, Cytokinesis and Signaling to the Cytoskeleton

Mohen Balasubramanian, University of Singapore
Fission Yeast as a Model for Eukaryotic and Prokaryotic Cytokinesis

Jay Groves, University of California, Berkeley
Spatial Organization and the Mechanics of Signal Transduction in Cell Membranes

Issei Mabuchi, Gakushuin University, Japan
Dynamics of the Contractile Ring During Cytokinesis

Edward Manser, Institute of Medical Biology, Singapore
How Cdc42-like CT Pases Signal to the Actin Cytoskeleton

Thursday, November 11, 2010

Morning Session
The Cytoskeleton and Cell Motility

Alexander Bershadsky, Weizmann Institute of Science, Israel
Mechanical and Biochemical Regulation of the Interplay Between Cell
Adhesion and the Actin Cytoskeleton

Gaudenz Danuser, Harvard Medical School
Probing Mechanical and Chemical Signal Integration in Cell Motility

Dorit Hanein, Burnham Institute for Medical Research
Seeing the Structural Organization of the Actin Cytoskeleton at the Leading Edge of Migrating Cells in Situ Electron Cryo-Tomography

Paul Matsudaira, National University of Singapore
The Mechanics of Epithelial Cell Migration

Pernille Rorth, Institute of Molecular and Cell Biology
Dynamics of Collective Cell Migration

Afternoon Session
The Cytoskeleton and Cell Motility

Iva Tolic-Norrelykke, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Nuclear Oscillations

Clare Waterman, NHLBI, NIH
Integrating Actin Dynamics with Adhesion in Cell Migration

Dan Fletcher, University of California, Berkeley
Mechanical Regulation of Actin Network Assembly

Birgit Lane, Institute of Medical Biology, Singapore
Polarized Remodeling of the Keratin Cytoskeleton in Response to Wounding: Localized Keratin Dynamics Revealed by Mutations in Keratinopathies

Cecile Sykes, Curie Institute, CNRS
Shells of Actin That Behave Like a Cell Cortex: A Biomimetic Experiment

Friday, November 12, 2010

Morning Session
The Cytoskeleton and Cell Motility

Anne Bernheim-Groswasser, Ben-Gurion University of the Negev, Israel
Cortactin: An Effector of Cell Propulsion

Pekka Lappalainen, Institute of Biotechnology, Finland
Mechanisms of Actin Stress Fiber Assembly in Motile Cells

Tom Pollard, Yale University
Quantitative Analysis of Arp2/3 Complex-Dependent Actin Assembly In Vitro
and In Vivo

Michael Dustin, New York University
Actin & Intermediate Filaments in Regulation of the Immune Response

Jan Faix, Hanover Medical School, Germany
Actin Filament Elongation by Ena/VASP Proteins

Afternoon Session
The Cytoskeleton and Cell Motility

Rong Li, Stowers Institute for Medical Research
The Role of the Arp2/3 Complex in Cellular Motility in Mouse

Laura Machesky, The Beatson Institute for Cancer Research, Scotland
Rac1 Controls Morphology, Motility and Growth of Melanoblasts

Shuh Narumiya, Kyoto University Faculty of Medicine, Japan
Phenotype Analysis of Mice Deficient in Actin Nucleator, mDia

W. James Nelson, Stanford University School of Medicine
Regulation of Actin Cytoskeleton Dynamics by the Cadherin-Catenin Complex

Dorothy Schafer, University of Virginia
Dynamin GTPase: a Novel Regulator of Actin Filament Networks
 

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